HitPredict

Interactor 1: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Interactor 2: HMGA2 (P52926)
High mobility group protein HMGI-C (High mobility group AT-hook protein 2)
Gene: HMGA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26045162
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0031492 - nucleosomal DNA binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 143 Hs			1 109
+	Mm
		650182 H2AX_MOUSE (1-143): 1.9e-73: 217: 97.20		HMGA2_MOUSE (1-109): 4.6e-41: 133: 95.41
+	Hs
		857503 H2A1J_HUMAN (1-128): 1.45e-66: 199: 92.19		HMGA2_HUMAN (1-109): 6.26e-43: 137: 100.00
+	Hs
		857497 H2A1C_HUMAN (1-129): 5.04e-66: 198: 92.25		HMGA2_HUMAN (1-109): 6.26e-43: 137: 100.00
+	Hs
		857476 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		HMGA2_HUMAN (1-109): 6.26e-43: 137: 100.00
+	Hs
		260809 H2AY_HUMAN (1-142): 1.74e-61: 194: 60.69		HMGA2_HUMAN (1-109): 6.26e-43: 137: 100.00
+	Mm
		857682 H2A3_MOUSE (1-129): 5.88e-66: 197: 91.47		HMGA2_MOUSE (1-109): 4.6e-41: 133: 95.41
+	Mm
		857885 H2AY_MOUSE (1-142): 1.04e-61: 195: 60.69		HMGA2_MOUSE (1-109): 4.6e-41: 133: 95.41