HitPredict

Interactor 1: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Interactor 2: BLM (P54132)
RecQ-like DNA helicase BLM (EC 5.6.2.4) (Bloom syndrome protein) (DNA 3'-5' helicase BLM) (DNA helicase, RecQ-like type 2) (RecQ2) (RecQ protein-like 3)
Gene: BLM

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	15364958, 29523790
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000724 - double-strand break repair via homologous recombination GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005657 - replication fork and 1 others more... GO:0006974 - DNA damage response
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 143 Hs			1 1417
+	Hs
		391611 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		BLM_HUMAN (1-1417): 0: 898: 100.00
+	Hs
		470305 H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47		BLM_HUMAN (1-1417): 0: 898: 100.00
+	Hs
		555458 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		WRN_HUMAN (487-1294): 3.74e-143: 475: 23.02
+	Hs
		801934 H2A1A_HUMAN (1-125): 8.26e-67: 200: 92.00		RECQ1_HUMAN (626-1233): 2.63e-131: 422: 34.75
+	Hs
		295151 H2A1A_HUMAN (1-125): 8.26e-67: 200: 92.00		RECQ4_HUMAN (661-1003): 2.2e-43: 175: 34.80
+	Hs
		294255 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		RECQ4_HUMAN (661-1003): 2.2e-43: 175: 34.80
+	Hs
		260686 H2AY_HUMAN (1-142): 1.74e-61: 194: 60.69		RECQ4_HUMAN (661-1003): 2.2e-43: 175: 34.80