HitPredict

Interactor 1: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Interactor 2: UBP14 (P54578)
Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.4.19.12) (Deubiquitinating enzyme 14) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14)
Gene: USP14

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30425250
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 143 Hs			1 494
+	Hs
		260811 H2AY_HUMAN (1-142): 1.74e-61: 194: 60.69		UBP14_HUMAN (1-494): 7.04e-147: 431: 100.00
+	Hs
		555508 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		U17L2_HUMAN (82-492): 7.98e-90: 285: 19.37
+	Hs
		391943 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		UBP36_HUMAN (65-482): 3.73e-90: 299: 17.54
+	Hs
		1312240 H2AJ_HUMAN (1-125): 5.62e-65: 195: 93.60		UBP36_HUMAN (65-482): 3.73e-90: 299: 17.54
+	Hs
		261028 H2AY_HUMAN (1-142): 1.74e-61: 194: 60.69		UBP36_HUMAN (65-482): 3.73e-90: 299: 17.54
+	Hs
		259285 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		UBP12_HUMAN (61-484): 1.14e-95: 295: 18.49
+	Hs
		777047 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		UBP8_HUMAN (42-489): 9.27e-89: 295: 18.07
+	Hs
		905382 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		UBP46_HUMAN (61-483): 1.58e-95: 295: 18.76
+	Hs
		391971 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		UBP22_HUMAN (66-487): 1.12e-91: 290: 19.03
+	Hs
		1087135 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		UBP22_HUMAN (66-487): 1.12e-91: 290: 19.03
+	Hs
		271018 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		UBP2_HUMAN (56-487): 5.71e-90: 288: 16.30
+	Hs
		271104 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		UBP2_HUMAN (56-487): 5.71e-90: 288: 16.30
+	Hs
		1151394 H2A2A_HUMAN (1-129): 7e-66: 197: 91.47		UBP21_HUMAN (29-486): 4.53e-88: 282: 16.80
+	Hs
		391991 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		UBP3_HUMAN (47-491): 2.12e-88: 282: 16.02
+	Hs
		391756 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		UBP51_HUMAN (35-486): 3.31e-86: 281: 18.26
+	Hs
		1087027 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		UBP51_HUMAN (35-486): 3.31e-86: 281: 18.26
+	Sc
		392501 H2A2_YEAST (16-124): 4.61e-53: 165: 82.57		UBP8_YEAST (105-485): 5.83e-38: 146: 20.51