HitPredict

Interactor 1: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Interactor 2: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	20000738, 20618440
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 143 Hs			1 245
+	Hs
		555389 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		555302 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		555315 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	Hs
		470333 H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		391557 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		470276 H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		391567 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60