HitPredict

Interactor 1: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Interactor 2: XPC (Q01831)
DNA repair protein complementing XP-C cells (Xeroderma pigmentosum group C-complementing protein) (p125)
Gene: XPC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	28514442, 28242625, 33961781, 19805520
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003684 - damaged DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0090734 - site of DNA damage
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 143 Hs			1 940
+	Hs
		967049 H2A2B_HUMAN (1-128): 3.43e-66: 198: 92.97		XPC_HUMAN (1-940): 0: 1158: 100.00
+	Hs
		391659 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		XPC_HUMAN (1-940): 0: 1158: 100.00
+	Hs
		470354 H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47		XPC_HUMAN (1-940): 0: 1158: 100.00
+	Hs
		967041 H2A2A_HUMAN (1-129): 7e-66: 197: 91.47		XPC_HUMAN (1-940): 0: 1158: 100.00
+	Hs
		967036 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		XPC_HUMAN (1-940): 0: 1158: 100.00
+	Hs
		260847 H2AY_HUMAN (1-142): 1.74e-61: 194: 60.69		XPC_HUMAN (1-940): 0: 1158: 100.00