HitPredict

Interactor 1: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Interactor 2: ENL (Q03111)
Protein ENL (YEATS domain-containing protein 1)
Gene: MLLT1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25921070
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 143 Hs			1 559
+	Hs
		974485 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		ENL_HUMAN (1-559): 7.97e-77: 255: 100.00
+	Hs
		555503 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		NIPBL_HUMAN (118-550): 1.81e-32: 135: 15.17
+	Hs
		555430 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		EP300_HUMAN (36-507): 4.29e-30: 128: 10.54
+	Hs
		998866 H2A2B_HUMAN (1-128): 3.43e-66: 198: 92.97		EP300_HUMAN (36-507): 4.29e-30: 128: 10.54
+	Hs
		391671 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		EP300_HUMAN (36-507): 4.29e-30: 128: 10.54
+	Hs
		998781 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		EP300_HUMAN (36-507): 4.29e-30: 128: 10.54
+	Hs
		391823 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		CBP_HUMAN (36-507): 4.66e-27: 118: 11.67
+	Mm
		101453 H2A3_MOUSE (1-129): 5.88e-66: 197: 91.47		F8VPR5_MOUSE (36-507): 8.7e-27: 117: 12.63
+	Mm
		70932 H2A3_MOUSE (1-129): 5.88e-66: 197: 91.47		EP300_MOUSE (36-507): 7.17e-26: 115: 10.44
+	Sc
		392095 H2A1_YEAST (16-142): 1.37e-53: 166: 75.59		TAF14_YEAST (6-176): 3.14e-26: 109: 15.91
+	Sc
		392383 H2A2_YEAST (16-124): 4.61e-53: 165: 82.57		TAF14_YEAST (6-176): 3.14e-26: 109: 15.91