HitPredict

Interactor 1: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Interactor 2: HNRPD (Q14103)
Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1)
Gene: HNRNPD

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26318153, 20000738
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 143 Hs			1 355
+	Hs
		1048189 H2A1A_HUMAN (1-125): 8.26e-67: 200: 92.00		HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00
+	Hs
		1048200 H2A1J_HUMAN (1-128): 1.45e-66: 199: 92.19		HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00
+	Hs
		1048135 H2A2B_HUMAN (1-128): 3.43e-66: 198: 92.97		HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00
+	Hs
		1048169 H2A1C_HUMAN (1-129): 5.04e-66: 198: 92.25		HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00
+	Hs
		1048183 H2A1H_HUMAN (1-128): 2.85e-66: 198: 92.19		HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00
+	Hs
		1048105 H2A2A_HUMAN (1-129): 7e-66: 197: 91.47		HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00
+	Hs
		1048120 H2A3_HUMAN (1-129): 5.88e-66: 197: 91.47		HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00
+	Hs
		391691 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00
+	Hs
		594845 H2A1D_HUMAN (1-129): 1.02e-65: 197: 90.70		HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00
+	Hs
		161956 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		HNRDL_HUMAN (89-355): 3.71e-56: 190: 62.63
+	Hs
		555618 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		ROAA_HUMAN (30-355): 3.41e-55: 185: 53.89
+	Hs
		391862 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		ROAA_HUMAN (30-355): 3.41e-55: 185: 53.89
+	Hs
		516349 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		PABP1_HUMAN (88-272): 2.1e-42: 157: 16.93
+	Hs
		555293 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		ROA2_HUMAN (98-277): 8.38e-39: 142: 41.40
+	Hs
		391681 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		PABP4_HUMAN (88-272): 4.65e-43: 159: 18.52
+	Hs
		391548 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		ROA2_HUMAN (98-277): 8.38e-39: 142: 41.40
+	Hs
		453126 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		ROA1_HUMAN (63-177): 4.79e-20: 92: 26.83
+	Hs
		474005 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		PAB4L_HUMAN (179-259): 1.74e-16: 81.7: 18.29
+	Hs
		555590 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		MSI2H_HUMAN (21-198): 1.49e-15: 78.3: 26.82
+	Hs
		391515 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		ROA1_HUMAN (63-177): 4.79e-20: 92: 26.83