HitPredict

Interactor 1: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Interactor 2: ZMAT1 (Q5H9K5)
Zinc finger matrin-type protein 1
Gene: ZMAT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 143 Hs			1 638
+	Hs
		555688 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		ZN346_HUMAN (32-275): 2.55e-69: 228: 26.32
+	Hs
		1216282 H2A2B_HUMAN (1-128): 3.43e-66: 198: 92.97		ZN346_HUMAN (32-275): 2.55e-69: 228: 26.32
+	Hs
		470607 H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47		ZN346_HUMAN (32-275): 2.55e-69: 228: 26.32
+	Hs
		1087131 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		ZN346_HUMAN (32-275): 2.55e-69: 228: 26.32
+	Hs
		261037 H2AY_HUMAN (1-142): 1.74e-61: 194: 60.69		ZN346_HUMAN (32-275): 2.55e-69: 228: 26.32
+	Hs
		555364 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		NEK4_HUMAN (5-49): 7.86e-11: 67.2: 53.33
+	Hs
		851642 H2A1A_HUMAN (1-125): 8.26e-67: 200: 92.00		NEK4_HUMAN (5-49): 7.86e-11: 67.2: 53.33
+	Hs
		851654 H2A1J_HUMAN (1-128): 1.45e-66: 199: 92.19		NEK4_HUMAN (5-49): 7.86e-11: 67.2: 53.33
+	Hs
		851576 H2A2B_HUMAN (1-128): 3.43e-66: 198: 92.97		NEK4_HUMAN (5-49): 7.86e-11: 67.2: 53.33
+	Hs
		851622 H2A1C_HUMAN (1-129): 5.04e-66: 198: 92.25		NEK4_HUMAN (5-49): 7.86e-11: 67.2: 53.33
+	Hs
		851636 H2A1H_HUMAN (1-128): 2.85e-66: 198: 92.19		NEK4_HUMAN (5-49): 7.86e-11: 67.2: 53.33
+	Hs
		391607 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		NEK4_HUMAN (5-49): 7.86e-11: 67.2: 53.33
+	Hs
		470303 H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47		NEK4_HUMAN (5-49): 7.86e-11: 67.2: 53.33
+	Hs
		594834 H2A1D_HUMAN (1-129): 1.02e-65: 197: 90.70		NEK4_HUMAN (5-49): 7.86e-11: 67.2: 53.33
+	Hs
		851543 H2A2A_HUMAN (1-129): 7e-66: 197: 91.47		NEK4_HUMAN (5-49): 7.86e-11: 67.2: 53.33
+	Hs
		851557 H2A3_HUMAN (1-129): 5.88e-66: 197: 91.47		NEK4_HUMAN (5-49): 7.86e-11: 67.2: 53.33
+	Hs
		851513 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		NEK4_HUMAN (5-49): 7.86e-11: 67.2: 53.33
+	Hs
		851664 H2AJ_HUMAN (1-125): 5.62e-65: 195: 93.60		NEK4_HUMAN (5-49): 7.86e-11: 67.2: 53.33