HitPredict

Interactor 1: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Interactor 2: SPT6H (Q7KZ85)
Transcription elongation factor SPT6 (hSPT6) (Histone chaperone suppressor of Ty6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein)
Gene: SUPT6H

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005654 - nucleoplasm GO:0042393 - histone binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 143 Hs			1 1726
+	Hs
		1182946 H2A1H_HUMAN (1-128): 2.85e-66: 198: 92.19		SPT6H_HUMAN (1-1726): 0: 1802: 100.00
+	Hs
		391758 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		SPT6H_HUMAN (1-1726): 0: 1802: 100.00
+	Hs
		260916 H2AY_HUMAN (1-142): 1.74e-61: 194: 60.69		SPT6H_HUMAN (1-1726): 0: 1802: 100.00
+	Sc
		392305 H2A2_YEAST (16-124): 4.61e-53: 165: 82.57		SPT6_YEAST (15-1512): 0: 812: 22.21
+	Hs
		470460 H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47		SRBD1_HUMAN (218-1212): 0: 597: 16.76
+	Hs
		555663 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		MDN1_HUMAN (6-680): 7.05e-92: 335: 12.40
+	Hs
		391929 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		MDN1_HUMAN (6-680): 7.05e-92: 335: 12.40