HitPredict

Interactor 1: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Interactor 2: PB1 (Q86U86)
Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D)
Gene: PBRM1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28242625
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BAH~Histone
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 143 Hs			1 1689
+	Hs
		391768 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		PB1_HUMAN (1-1689): 0: 1223: 100.00
+	Hs
		1087035 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		PB1_HUMAN (1-1689): 0: 1223: 100.00
+	Hs
		260921 H2AY_HUMAN (1-142): 1.74e-61: 194: 60.69		PB1_HUMAN (1-1689): 0: 1223: 100.00
+	Hs
		641230 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		DNMT1_HUMAN (301-1361): 1.76e-75: 280: 12.20
+	Xl
		945507 H2AX_XENLA (1-143): 4.46e-67: 201: 84.62		P79922_XENLA (585-1361): 7.33e-72: 268: 13.31
+	Xl
		420791 H2A1_XENLA (1-129): 8.72e-66: 197: 89.92		P79922_XENLA (585-1361): 7.33e-72: 268: 13.31
+	Hs
		555470 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		BRD3_HUMAN (358-959): 6.75e-48: 186: 12.76
+	Hs
		1087066 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		PHIP_HUMAN (480-1024): 4.44e-53: 207: 13.50
+	Hs
		1067038 H2A2B_HUMAN (1-128): 3.43e-66: 198: 92.97		BRD3_HUMAN (358-959): 6.75e-48: 186: 12.76
+	Hs
		1067005 H2A2A_HUMAN (1-129): 7e-66: 197: 91.47		BRD3_HUMAN (358-959): 6.75e-48: 186: 12.76
+	Hs
		1066979 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		BRD3_HUMAN (358-959): 6.75e-48: 186: 12.76
+	Hs
		260889 H2AY_HUMAN (1-142): 1.74e-61: 194: 60.69		BRD3_HUMAN (358-959): 6.75e-48: 186: 12.76
+	Hs
		555299 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		BRD2_HUMAN (2-169): 7.14e-20: 98.6: 15.29
+	Hs
		631492 H2A2B_HUMAN (1-128): 3.43e-66: 198: 92.97		BRD2_HUMAN (2-169): 7.14e-20: 98.6: 15.29
+	Hs
		391554 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		BRD2_HUMAN (2-169): 7.14e-20: 98.6: 15.29
+	Hs
		260758 H2AY_HUMAN (1-142): 1.74e-61: 194: 60.69		BRD2_HUMAN (2-169): 7.14e-20: 98.6: 15.29
+	Hs
		555359 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		SMCA4_HUMAN (764-881): 7.55e-11: 69.5: 23.58
+	Hs
		555358 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		SMCA2_HUMAN (794-881): 2.15e-09: 64.9: 26.09
+	Sp
		391996 H2A1_SCHPO (1-127): 1.34e-53: 166: 81.40		YK82_SCHPO (2-153): 1.98e-21: 103: 16.88
+	Hs
		260802 H2AY_HUMAN (1-142): 1.74e-61: 194: 60.69		SMCA4_HUMAN (764-881): 7.55e-11: 69.5: 23.58