HitPredict

Interactor 1: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Interactor 2: IPO9 (Q96P70)
Importin-9 (Imp9) (Ran-binding protein 9) (RanBP9)
Gene: IPO9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~IBN_N
Common GO terms	GO:0042393 - histone binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 143 Hs			1 1041
+	Hs
		1151371 H2A2A_HUMAN (1-129): 7e-66: 197: 91.47		IPO9_HUMAN (1-1041): 0: 718: 100.00
+	Hs
		391848 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		IPO9_HUMAN (1-1041): 0: 718: 100.00
+	Hs
		470508 H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47		IPO9_HUMAN (1-1041): 0: 718: 100.00
+	Hs
		1087085 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		IPO9_HUMAN (1-1041): 0: 718: 100.00
+	Hs
		1299129 H2AJ_HUMAN (1-125): 5.62e-65: 195: 93.60		IPO9_HUMAN (1-1041): 0: 718: 100.00
+	Hs
		391615 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		XPO2_HUMAN (17-882): 4.31e-144: 457: 14.30
+	Hs
		155512 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		TNPO2_HUMAN (14-878): 1.92e-140: 445: 13.05
+	Sc
		392159 H2A1_YEAST (16-142): 1.37e-53: 166: 75.59		IMB5_YEAST (23-1038): 8.56e-125: 407: 18.95
+	Sc
		392507 H2A2_YEAST (16-124): 4.61e-53: 165: 82.57		IMB5_YEAST (23-1038): 8.56e-125: 407: 18.95