Interactor 1: F261 (P16118)
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 (6PF-2-K/Fru-2,6-P2ase 1) (PFK/FBPase 1) (6PF-2-K/Fru-2,6-P2ase liver isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]
Gene: PFKFB1
Interactor 2: F261 (P16118)
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 (6PF-2-K/Fru-2,6-P2ase 1) (PFK/FBPase 1) (6PF-2-K/Fru-2,6-P2ase liver isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]
Gene: PFKFB1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.80 | 1.00 | 0.898 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25416956, 32296183, unassigned1304, 12379646 |
| Identification Methods | two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid, x-ray crystallography |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | 6PF2K~6PF2K, 6PF2K~His_Phos_1, His_Phos_1~His_Phos_1 |
| Common GO terms | GO:0003873 - 6-phosphofructo-2-kinase activity GO:0004331 - fructose-2,6-bisphosphate 2-phosphatase activity GO:0005524 - ATP binding GO:0005829 - cytosol GO:0006000 - fructose metabolic process and 13 others more... |
| Homologous interactions | 14 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
