HitPredict

Interactor 1: VATB (P16140)
V-type proton ATPase subunit B (V-ATPase subunit B) (V-ATPase 57 kDa subunit) (Vacuolar proton pump subunit B)
Gene: VMA2

Interactor 2: VATH (P41807)
V-type proton ATPase subunit H (V-ATPase subunit H) (V-ATPase 54 kDa subunit) (Vacuolar proton pump subunit H)
Gene: VMA13

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.705

The method score is based on:

Property	Details
Experiments	16554755, 37968396, 18708638, 19299516, 23071676
Identification Methods	affinity chromatography technology, two hybrid, unspecified method, tandem affinity purification
Interaction Type	physical association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0000221 - vacuolar proton-transporting V-type ATPase, V1 domain GO:0000329 - fungal-type vacuole membrane GO:0007035 - vacuolar acidification GO:0016471 - vacuolar proton-transporting V-type ATPase complex and 5 others more... GO:0033176 - proton-transporting V-type ATPase complex GO:0046961 - proton-transporting ATPase activity, rotational mechanism GO:0048388 - endosomal lumen acidification GO:0061795 - Golgi lumen acidification GO:1902600 - proton transmembrane transport
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	517
Sc

1	478

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024