HitPredict

Interactor 1: VATB (P16140)
V-type proton ATPase subunit B (V-ATPase subunit B) (V-ATPase 57 kDa subunit) (Vacuolar proton pump subunit B)
Gene: VMA2

Interactor 2: WDR59 (Q03897)
Maintenance of telomere capping protein 5 (SEH-associated protein 3)
Gene: MTC5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	11805837, 25073740
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000329 - fungal-type vacuole membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 517 Sc			1 1148
+	Sc
		423903 ATPA_YEAST (5-512): 9.74e-156: 456: 21.18		WDR59_YEAST (1-1148): 0: 831: 100.00
+	Sc
		342100 ATPB_YEAST (29-448): 2.03e-151: 444: 23.42		WDR59_YEAST (1-1148): 0: 831: 100.00
+	Sc
		556114 VATB_YEAST (1-517): 0: 611: 100.00		COPB2_YEAST (2-364): 3.6e-36: 150: 11.14
+	Hs
		636838 ATPA_HUMAN (7-514): 2.94e-163: 476: 22.27		LIS1_HUMAN (154-488): 3.85e-46: 173: 12.24
+	Sc
		423865 ATPA_YEAST (5-512): 9.74e-156: 456: 21.18		COPB2_YEAST (2-364): 3.6e-36: 150: 11.14
+	Hs
		637013 ATPA_HUMAN (7-514): 2.94e-163: 476: 22.27		FBXW7_HUMAN (230-532): 4.61e-19: 95: 5.83
+	Ce
		954126 ATPA_CAEEL (4-514): 1.59e-154: 453: 21.36		LIN53_CAEEL (23-187): 2.27e-24: 109: 16.02
+	Hs
		636882 ATPA_HUMAN (7-514): 2.94e-163: 476: 22.27		GBB2_HUMAN (295-492): 6.76e-13: 73.4: 10.00
+	Hs
		636877 ATPA_HUMAN (7-514): 2.94e-163: 476: 22.27		WDR5_HUMAN (1-97): 8.99e-10: 63.7: 13.59
+	Hs
		415434 ATPB_HUMAN (29-446): 1.85e-148: 437: 24.00		FBXW7_HUMAN (230-532): 4.61e-19: 95: 5.83
+	Hs
		415288 ATPB_HUMAN (29-446): 1.85e-148: 437: 24.00		WDR5_HUMAN (1-97): 8.99e-10: 63.7: 13.59