Interactor 1: ITB4 (P16144)
Integrin beta-4 (GP150) (CD antigen CD104)
Gene: ITGB4

Interactor 2: CBL (P22681)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING finger protein 55) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL)
Gene: CBL

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 36470425
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Cbl_N~fn3, Cbl_N2~fn3, Cbl_N3~fn3
Common GO terms GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 1822
Hs

1 906
+ Mm
+ Mm
+ Mm
+ Ce

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Last updated: 15 Jul 2024