HitPredict

Interactor 1: CREB1 (P16220)
Cyclic AMP-responsive element-binding protein 1 (CREB-1) (cAMP-responsive element-binding protein 1)
Gene: CREB1

Interactor 2: KAPCA (P17612)
cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)
Gene: PRKACA

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.651

Property	Details
Experiments	12805224, 11500364, 37501933
Identification Methods	enzymatic study, pull down, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006468 - protein phosphorylation
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 327 Hs			1 351
+	Hs
		556790 CREB1_HUMAN (1-327): 6.86e-146: 415: 100.00		AKT1_HUMAN (7-347): 2.89e-149: 430: 38.79
+	Hs
		556864 CREB1_HUMAN (1-327): 6.86e-146: 415: 100.00		KGP1_HUMAN (41-334): 2.3e-89: 283: 46.15
+	Hs
		116967 CREB1_HUMAN (1-327): 6.86e-146: 415: 100.00		SGK1_HUMAN (34-342): 1.03e-85: 267: 42.54