HitPredict

Interactor 1: CREB1 (P16220)
Cyclic AMP-responsive element-binding protein 1 (CREB-1) (cAMP-responsive element-binding protein 1)
Gene: CREB1

Interactor 2: ATF1 (P18846)
Cyclic AMP-dependent transcription factor ATF-1 (cAMP-dependent transcription factor ATF-1) (Activating transcription factor 1) (Protein TREB36)
Gene: ATF1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.812

The method score is based on:

Property Details
Experiments 25609649, 20102225
Identification Methods affinity chromatography technology, peptide array, tandem affinity purification, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains bZIP_1~bZIP_1
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
and 8 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 327
Hs

1 271
+ Mm
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+ Hs
+ Hs
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+ Nv
+ Hs
+ Ci
+ Ce
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024