Interactor 1: CREB1 (P16220)
Cyclic AMP-responsive element-binding protein 1 (CREB-1) (cAMP-responsive element-binding protein 1)
Gene: CREB1

Interactor 2: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.971

The method score is based on:

Property Details
Experiments 10506141, 33846793, 7870179, 26944191, 12665587, 21212407, 11313407, 22787115, 21268077, 17476304
Identification Methods affinity chromatography technology, far western blotting, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains KIX~pKID
Common GO terms GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0007623 - circadian rhythm
GO:0045893 - positive regulation of DNA-templated transcription
and 3 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 327
Hs

1 2414
+ Mm
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024