HitPredict

Interactor 1: PGFRA (P16234)
Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)
Gene: PDGFRA

Interactor 2: FGFR4 (P22455)
Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)
Gene: FGFR4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.63 1.00 0.799

The method score is based on:

Property Details
Experiments 28205554, 33961781
Identification Methods fluorescent resonance energy transfer, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains I-set~I-set, Ig_3~I-set, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr
Common GO terms GO:0005524 - ATP binding
GO:0005794 - Golgi apparatus
GO:0005886 - plasma membrane
GO:0008284 - positive regulation of cell population proliferation
GO:0018108 - peptidyl-tyrosine phosphorylation
and 3 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1089
Hs

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Last updated: 15 Jul 2024