HitPredict

Interactor 1: PGFRA (P16234)
Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)
Gene: PDGFRA

Interactor 2: SRPK1 (Q96SB4)
SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1)
Gene: SRPK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.53 1.00 0.735

The method score is based on:

Property Details
Experiments 23602568
Identification Methods enzymatic study, protein kinase assay
Interaction Type direct interaction, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains I-set~Pkinase, PK_Tyr_Ser-Thr~Pkinase
Common GO terms GO:0004672 - protein kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024