HitPredict

Interactor 1: NCK1 (P16333)
SH2/SH3 adapter protein NCK1 (Cytoplasmic protein NCK1) (NCK adapter protein 1) (Nck-1) (SH2/SH3 adapter protein NCK-alpha)
Gene: NCK1

Interactor 2: H2B1D (P58876)
Histone H2B type 1-D (H2B-clustered histone 5) (HIRA-interacting protein 2) (Histone H2B.1 B) (Histone H2B.b) (H2B/b)
Gene: H2BC5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 377 Hs			1 126
+	Hs
		557845 NCK1_HUMAN (1-377): 1.69e-98: 299: 100.00		U3KQK0_HUMAN (1-126): 2.86e-55: 171: 99.21
+	Hs
		557738 NCK1_HUMAN (1-377): 1.69e-98: 299: 100.00		H2B3B_HUMAN (1-126): 2.67e-51: 160: 95.24
+	Hs
		924623 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		H2B2F_HUMAN (1-126): 3.9e-54: 167: 97.62
+	Hs
		924820 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		H2B1M_HUMAN (1-126): 4.45e-54: 167: 96.83
+	Hs
		924770 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		H2B1H_HUMAN (1-126): 8.88e-54: 166: 98.41
+	Hs
		241496 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		H2B1K_HUMAN (1-126): 2.11e-53: 165: 98.41
+	Hs
		883010 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		H2BFS_HUMAN (1-126): 1.64e-53: 165: 96.83
+	Hs
		886077 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		H2B1D_HUMAN (1-126): 2.74e-53: 165: 100.00
+	Hs
		918279 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		H2B1C_HUMAN (1-126): 1.71e-53: 165: 99.21
+	Hs
		924819 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		H2B1N_HUMAN (1-126): 3.49e-53: 164: 99.21
+	Hs
		924821 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		H2B1L_HUMAN (1-126): 3.72e-52: 162: 97.62