HitPredict

Interactor 1: NCK1 (P16333)
SH2/SH3 adapter protein NCK1 (Cytoplasmic protein NCK1) (NCK adapter protein 1) (Nck-1) (SH2/SH3 adapter protein NCK-alpha)
Gene: NCK1

Interactor 2: RL40 (P62987)
Ubiquitin-ribosomal protein eL40 fusion protein (CEP52) (Ubiquitin A-52 residue ribosomal protein fusion product 1) [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40 (60S ribosomal protein L40)]
Gene: UBA52

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	21900206
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	SH3_1~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005783 - endoplasmic reticulum GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 377 Hs			1 128
+	Hs
		557653 NCK1_HUMAN (1-377): 1.69e-98: 299: 100.00		RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70
+	Hs
		924264 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		RL40_HUMAN (1-128): 1.05e-56: 174: 100.00
+	Hs
		924433 VAV3_HUMAN (1-58): 1.16e-12: 71.4: 24.59		RL40_HUMAN (1-128): 1.05e-56: 174: 100.00
+	Dm
		547942 SRC42_DROME (6-127): 2.31e-18: 88.3: 24.19		RS27A_DROME (1-77): 3.98e-38: 127: 98.70
+	Hs
		923946 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70
+	Hs
		474986 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		UBB_HUMAN (1-76): 1.52e-33: 118: 100.00