HitPredict

Interactor 1: NCK1 (P16333)
SH2/SH3 adapter protein NCK1 (Cytoplasmic protein NCK1) (NCK adapter protein 1) (Nck-1) (SH2/SH3 adapter protein NCK-alpha)
Gene: NCK1

Interactor 2: SOS2 (Q07890)
Son of sevenless homolog 2 (SOS-2)
Gene: SOS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 33961781, 17474147
Identification Methods affinity chromatography technology, peptide array, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PH~SH3_1, RhoGEF~SH3_1
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 377
Hs

1 1332
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024