HitPredict

Interactor 1: NCK1 (P16333)
SH2/SH3 adapter protein NCK1 (Cytoplasmic protein NCK1) (NCK adapter protein 1) (Nck-1) (SH2/SH3 adapter protein NCK-alpha)
Gene: NCK1

Interactor 2: AKAP6 (Q13023)
A-kinase anchor protein 6 (AKAP-6) (A-kinase anchor protein 100 kDa) (AKAP 100) (Protein kinase A-anchoring protein 6) (PRKA6) (mAKAP)
Gene: AKAP6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 377 Hs			1 2319
+	Hs
		655345 P85A_HUMAN (241-376): 1.37e-22: 101: 19.57		AKAP6_HUMAN (1-2319): 0: 2654: 100.00
+	Hs
		412161 FYN_HUMAN (7-173): 7.47e-21: 96: 15.39		AKAP6_HUMAN (1-2319): 0: 2654: 100.00
+	Hs
		522946 SRC_HUMAN (5-114): 1.61e-15: 79.7: 22.32		AKAP6_HUMAN (1-2319): 0: 2654: 100.00
+	Hs
		924531 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		AKAP6_HUMAN (1-2319): 0: 2654: 100.00
+	Rn
		192738 SRBS2_RAT (3-162): 4.86e-25: 109: 28.05		SPTN1_RAT (913-1371): 1.45e-24: 115: 12.15
+	Hs
		129277 P85B_HUMAN (100-376): 1.85e-21: 98.3: 16.61		SPTB2_HUMAN (620-1335): 3.36e-22: 107: 8.79
+	Hs
		298957 SRBS2_HUMAN (64-287): 1.79e-23: 104: 18.26		MYH9_HUMAN (877-1373): 1.07e-19: 99.3: 10.37
+	Hs
		1045423 ITSN1_HUMAN (5-286): 1.55e-16: 83.6: 17.07		SPTN1_HUMAN (913-1371): 1.2e-24: 115: 12.58
+	Hs
		129220 P85B_HUMAN (100-376): 1.85e-21: 98.3: 16.61		MYH9_HUMAN (877-1373): 1.07e-19: 99.3: 10.37
+	Hs
		412058 FYN_HUMAN (7-173): 7.47e-21: 96: 15.39		MYH9_HUMAN (877-1373): 1.07e-19: 99.3: 10.37
+	Hs
		924555 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		SPTN1_HUMAN (913-1371): 1.2e-24: 115: 12.58
+	Hs
		963335 ITSN1_HUMAN (5-286): 1.55e-16: 83.6: 17.07		SPTB2_HUMAN (620-1335): 3.36e-22: 107: 8.79
+	Hs
		924482 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		SPTB2_HUMAN (620-1335): 3.36e-22: 107: 8.79
+	Hs
		724756 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		MYH9_HUMAN (877-1373): 1.07e-19: 99.3: 10.37
+	Hs
		111443 J3QRU1_HUMAN (112-218): 4.03e-11: 66.5: 19.27		MYH9_HUMAN (877-1373): 1.07e-19: 99.3: 10.37
+	Hs
		433272 YES_HUMAN (112-218): 4.18e-11: 66.1: 19.27		MYH9_HUMAN (877-1373): 1.07e-19: 99.3: 10.37
+	Hs
		974083 ITSN1_HUMAN (5-286): 1.55e-16: 83.6: 17.07		DYST_HUMAN (268-1371): 1.25e-12: 76.2: 11.00
+	Hs
		924491 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		DYST_HUMAN (268-1371): 1.25e-12: 76.2: 11.00
+	Hs
		1078871 ITSN1_HUMAN (5-286): 1.55e-16: 83.6: 17.07		SYNE1_HUMAN (723-1252): 8.62e-11: 70.3: 12.82
+	Hs
		974160 ITSN2_HUMAN (7-85): 2.68e-12: 70.6: 24.05		DYST_HUMAN (268-1371): 1.25e-12: 76.2: 11.00