HitPredict

Interactor 1: NCK1 (P16333)
SH2/SH3 adapter protein NCK1 (Cytoplasmic protein NCK1) (NCK adapter protein 1) (Nck-1) (SH2/SH3 adapter protein NCK-alpha)
Gene: NCK1

Interactor 2: LRFN4 (Q6PJG9)
Leucine-rich repeat and fibronectin type-III domain-containing protein 4
Gene: LRFN4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	28514442, 33961781, 22677168
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	SH2~fn3, LRR_8~SH2
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 377 Hs			1 635
+	Hs
		209085 NCK2_HUMAN (1-376): 7.1e-90: 277: 68.24		LRFN4_HUMAN (17-635): 1.88e-142: 430: 100.00
+	Hs
		655488 P85A_HUMAN (241-376): 1.37e-22: 101: 19.57		FLRT1_HUMAN (3-198): 1.1e-33: 138: 24.26
+	Hs
		129344 P85B_HUMAN (100-376): 1.85e-21: 98.3: 16.61		FLRT1_HUMAN (3-198): 1.1e-33: 138: 24.26
+	Hs
		433494 YES_HUMAN (112-218): 4.18e-11: 66.1: 19.27		FLRT1_HUMAN (3-198): 1.1e-33: 138: 24.26