HitPredict

Interactor 1: NCK1 (P16333)
SH2/SH3 adapter protein NCK1 (Cytoplasmic protein NCK1) (NCK adapter protein 1) (Nck-1) (SH2/SH3 adapter protein NCK-alpha)
Gene: NCK1

Interactor 2: DLX4 (Q92988)
Homeobox protein DLX-4 (Beta protein 1) (Homeobox protein DLX-7) (Homeobox protein DLX-8)
Gene: DLX4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 377 Hs			1 240
+	Hs
		557620 NCK1_HUMAN (1-377): 1.69e-98: 299: 100.00		HXC8_HUMAN (7-185): 4.28e-29: 111: 21.16
+	Hs
		209011 NCK2_HUMAN (1-376): 7.1e-90: 277: 68.24		MEOX2_HUMAN (15-188): 1.44e-32: 121: 25.86
+	Hs
		209081 NCK2_HUMAN (1-376): 7.1e-90: 277: 68.24		Q6FHY5_HUMAN (15-188): 1.41e-32: 121: 25.86
+	Hs
		655331 P85A_HUMAN (241-376): 1.37e-22: 101: 19.57		DLX2_HUMAN (25-210): 6.89e-43: 149: 40.10
+	Hs
		655436 P85A_HUMAN (241-376): 1.37e-22: 101: 19.57		DLX4_HUMAN (1-240): 5.03e-42: 144: 100.00
+	Hs
		412292 FYN_HUMAN (7-173): 7.47e-21: 96: 15.39		DLX4_HUMAN (1-240): 5.03e-42: 144: 100.00
+	Hs
		523097 SRC_HUMAN (5-114): 1.61e-15: 79.7: 22.32		DLX4_HUMAN (1-240): 5.03e-42: 144: 100.00
+	Hs
		924769 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		DLX4_HUMAN (1-240): 5.03e-42: 144: 100.00
+	Hs
		412088 FYN_HUMAN (7-173): 7.47e-21: 96: 15.39		MEOX2_HUMAN (15-188): 1.44e-32: 121: 25.86
+	Hs
		412230 FYN_HUMAN (7-173): 7.47e-21: 96: 15.39		Q6FHY5_HUMAN (15-188): 1.41e-32: 121: 25.86
+	Hs
		412045 FYN_HUMAN (7-173): 7.47e-21: 96: 15.39		HXC8_HUMAN (7-185): 4.28e-29: 111: 21.16
+	Hs
		924721 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		LMX1A_HUMAN (81-239): 7.08e-30: 116: 20.25
+	Hs
		522809 SRC_HUMAN (5-114): 1.61e-15: 79.7: 22.32		HXC8_HUMAN (7-185): 4.28e-29: 111: 21.16
+	Hs
		678897 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		HXC8_HUMAN (7-185): 4.28e-29: 111: 21.16
+	Ce
		106223 SRC2_CAEEL (1-66): 6.4e-11: 65.6: 33.82		VAB3_CAEEL (65-238): 1.03e-29: 116: 19.54