HitPredict

Interactor 1: NCK1 (P16333)
SH2/SH3 adapter protein NCK1 (Cytoplasmic protein NCK1) (NCK adapter protein 1) (Nck-1) (SH2/SH3 adapter protein NCK-alpha)
Gene: NCK1

Interactor 2: SEM6A (Q9H2E6)
Semaphorin-6A (Semaphorin VIA) (Sema VIA) (Semaphorin-6A-1) (SEMA6A-1)
Gene: SEMA6A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 377 Hs			1 1030
+	Hs
		209166 NCK2_HUMAN (1-376): 7.1e-90: 277: 68.24		SEM6A_HUMAN (1-1030): 0: 1031: 100.00
+	Hs
		299000 SRBS2_HUMAN (64-287): 1.79e-23: 104: 18.26		SEM6A_HUMAN (1-1030): 0: 1031: 100.00
+	Hs
		1329264 ITSN2_HUMAN (7-85): 2.68e-12: 70.6: 24.05		SEM6A_HUMAN (1-1030): 0: 1031: 100.00
+	Hs
		259519 NCK1_HUMAN (1-377): 1.69e-98: 299: 100.00		SEM7A_HUMAN (65-618): 1.83e-142: 443: 26.82
+	Hs
		195974 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		PLXB1_HUMAN (45-949): 1.68e-156: 512: 16.80
+	Hs
		259518 FYN_HUMAN (7-173): 7.47e-21: 96: 15.39		SEM7A_HUMAN (65-618): 1.83e-142: 443: 26.82
+	Hs
		259523 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		SEM7A_HUMAN (65-618): 1.83e-142: 443: 26.82