HitPredict

Interactor 1: RPB3 (P16370)
DNA-directed RNA polymerase II subunit RPB3 (RNA polymerase II subunit 3) (RNA polymerase II subunit B3) (B44.5) (DNA-directed RNA polymerase II 45 kDa polypeptide)
Gene: RPB3

Interactor 2: SPT5 (P27692)
Transcription elongation factor SPT5 (Chromatin elongation factor SPT5)
Gene: SPT5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	1.00	0.978

Property	Details
Experiments	12556496, 16085932, 16429126, 16554755, 28043953, 29133017, 34543624, 33888559, 34592154, 37968396, 21048197, 23418395, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	KOW~RNA_pol_L
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0006368 - transcription elongation by RNA polymerase II
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 318 Sc			1 1063
+	Hs
		123849 RPB3_HUMAN (6-270): 4.25e-119: 345: 45.19		SPT5H_HUMAN (125-1060): 0: 781: 23.54
+	Sc
		429650 RPAC1_YEAST (3-258): 3.25e-89: 271: 23.31		SPT5_YEAST (1-1063): 0: 803: 100.00
+	Sc
		558308 RPB3_YEAST (1-318): 3.91e-173: 484: 100.00		MDN1_YEAST (2-545): 2.03e-51: 200: 11.29
+	At
		1107282 RPD3B_ARATH (6-269): 1.86e-96: 289: 34.33		PPR29_ARATH (758-1061): 3.11e-36: 150: 13.20