Interactor 1: GROU (P16371)
Protein groucho (Enhancer of split m9/10 protein) (E(spl)m9/10)
Gene: gro

Interactor 2: HDAC1 (Q94517)
Histone deacetylase HDAC1 (HD) (EC 3.5.1.98)
Gene: HDAC1

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 0.60 0.625

The method score is based on:

Property Details
Experiments 10485845, 15802274, unassigned4
Identification Methods affinity chromatography technology, experimental interaction detection
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006355 - regulation of DNA-templated transcription
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 730
Dm

1 521
+ Hs
+ Hs
+ Mm
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+ Ce
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+ Dm
+ Dm
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+ Hs
+ Hs
+ Hs
+ Hs
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+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024