HitPredict

Interactor 1: GROU (P16371)
Protein groucho (Enhancer of split m9/10 protein) (E(spl)m9/10)
Gene: gro

Interactor 2: Q9N693 (Q9N693)
Brakeless-B (Scribbler long isoform) (Scribbler, isoform D) (Scribbler, isoform H)
Gene: sbb

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17571073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003714 - transcription corepressor activity GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 730 Dm			1 2302
+	Dm
		558389 GROU_DROME (1-730): 4.17e-172: 513: 100.00		Q9GRA9_DROME (7-2302): 2.02e-164: 565: 99.65
+	Hs
		980906 TLE3_HUMAN (1-730): 2.82e-146: 447: 57.27		ZN608_HUMAN (704-1206): 3.03e-36: 153: 29.33
+	Hs
		164216 TLE3_HUMAN (1-730): 2.82e-146: 447: 57.27		ZN609_HUMAN (646-2015): 2.98e-34: 146: 16.55
+	Hs
		980830 TLE3_HUMAN (1-730): 2.82e-146: 447: 57.27		CBP_HUMAN (1197-1847): 4.59e-17: 90.8: 14.79
+	Hs
		980660 TLE1_HUMAN (1-730): 6.59e-154: 467: 60.08		RERE_HUMAN (686-1664): 5.08e-11: 70.5: 8.25
+	Hs
		980896 TLE3_HUMAN (1-730): 2.82e-146: 447: 57.27		RERE_HUMAN (686-1664): 5.08e-11: 70.5: 8.25
+	Hs
		980850 TLE3_HUMAN (1-730): 2.82e-146: 447: 57.27		MINT_HUMAN (1199-2158): 1.81e-09: 65.7: 10.44
+	Hs
		993473 TLE5_HUMAN (1-197): 8.88e-84: 265: 49.51		ANR11_HUMAN (1363-2113): 3.85e-11: 71.1: 11.86
+	Dm
		1358850 WDS_DROME (565-728): 5.12e-51: 183: 19.76		NUP98_DROME (28-746): 1.44e-32: 141: 13.24
+	Hs
		903598 WDR5_HUMAN (615-729): 8.81e-35: 137: 18.80		ZN608_HUMAN (704-1206): 3.03e-36: 153: 29.33
+	Hs
		1302927 NLE1_HUMAN (326-644): 1.39e-62: 218: 12.53		MINT_HUMAN (1199-2158): 1.81e-09: 65.7: 10.44
+	Hs
		164257 SNR40_HUMAN (566-728): 3.08e-32: 130: 20.96		ZN609_HUMAN (646-2015): 2.98e-34: 146: 16.55
+	Hs
		903229 WDR5_HUMAN (615-729): 8.81e-35: 137: 18.80		NCOA6_HUMAN (796-2289): 2.9e-27: 124: 8.96
+	Hs
		903405 WDR5_HUMAN (615-729): 8.81e-35: 137: 18.80		CBP_HUMAN (1197-1847): 4.59e-17: 90.8: 14.79
+	Hs
		929460 RACK1_HUMAN (564-728): 1.59e-36: 141: 15.98		MDC1_HUMAN (1378-2192): 1.97e-15: 85.4: 11.02
+	Mm
		903669 WDR5_MOUSE (615-729): 8.81e-35: 137: 18.80		KMT2C_MOUSE (1526-2219): 1.35e-14: 82.7: 12.36
+	Dm
		113977 GBLP_DROME (564-728): 2.96e-36: 141: 15.00		M9PB30_DROME (1839-2302): 3.1e-13: 78.3: 10.78
+	Hs
		1056932 SNR40_HUMAN (566-728): 3.08e-32: 130: 20.96		MDC1_HUMAN (1378-2192): 1.97e-15: 85.4: 11.02
+	Hs
		903576 WDR5_HUMAN (615-729): 8.81e-35: 137: 18.80		RERE_HUMAN (686-1664): 5.08e-11: 70.5: 8.25
+	Hs
		903374 WDR5_HUMAN (615-729): 8.81e-35: 137: 18.80		KMT2C_HUMAN (1718-2254): 9.57e-11: 70: 13.25