HitPredict

Interactor 1: GNAO (P16378)
G protein alpha o subunit (Guanine nucleotide-binding protein G(o) subunit alpha 47A)
Gene: Galphao

Interactor 2: AXN (Q9V407)
Axin (Axis inhibition protein) (d-Axin) (dAxin)
Gene: AXN

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	19705439
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	G-alpha~RGS
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0007507 - heart development
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 354 Dm			1 745
+	Hs
		158597 GNAI2_HUMAN (1-354): 9.73e-173: 485: 67.89		RGS12_HUMAN (35-663): 5.19e-136: 437: 16.60
+	Hs
		158608 GNAI1_HUMAN (1-354): 2.77e-172: 484: 69.01		RGS12_HUMAN (35-663): 5.19e-136: 437: 16.60
+	Hs
		207505 GNAI2_HUMAN (1-354): 9.73e-173: 485: 67.89		RGS14_HUMAN (25-560): 1.24e-106: 338: 15.44
+	Hs
		277782 GNAO_HUMAN (1-354): 6.79e-174: 489: 82.20		RGS9_HUMAN (19-345): 1.66e-71: 248: 15.84
+	Hs
		450989 GNAO_HUMAN (1-354): 6.79e-174: 489: 82.20		RGS4_HUMAN (4-196): 3.79e-64: 214: 17.62
+	Hs
		391358 GNAI2_HUMAN (1-354): 9.73e-173: 485: 67.89		RGS4_HUMAN (4-196): 3.79e-64: 214: 17.62
+	Rn
		500350 GNAI1_RAT (1-354): 3.85e-172: 484: 69.01		RGS4_RAT (4-196): 3.64e-64: 214: 18.14
+	Rn
		834945 GNAO_RAT (1-354): 5.71e-172: 484: 81.07		RGS4_RAT (4-196): 3.64e-64: 214: 18.14
+	Hs
		391357 GNAI2_HUMAN (1-354): 9.73e-173: 485: 67.89		RGS3_HUMAN (12-181): 1.22e-55: 209: 20.00
+	Hs
		391473 GNAI2_HUMAN (1-354): 9.73e-173: 485: 67.89		RGS18_HUMAN (20-186): 7.9e-62: 209: 22.16
+	Hs
		283160 GNAO_HUMAN (1-354): 6.79e-174: 489: 82.20		RGS20_HUMAN (8-179): 2.78e-58: 204: 19.77
+	Hs
		283156 GNAI2_HUMAN (1-354): 9.73e-173: 485: 67.89		RGS20_HUMAN (8-179): 2.78e-58: 204: 19.77
+	Hs
		182443 GNAO_HUMAN (1-354): 6.79e-174: 489: 82.20		RGS5_HUMAN (32-173): 5.67e-59: 199: 25.35
+	Hs
		180653 GNAO_HUMAN (1-354): 6.79e-174: 489: 82.20		RGS16_HUMAN (1-171): 2.61e-57: 195: 17.78
+	Hs
		182439 GNAI2_HUMAN (1-354): 9.73e-173: 485: 67.89		RGS5_HUMAN (32-173): 5.67e-59: 199: 25.35
+	Hs
		158580 GNAI2_HUMAN (1-354): 9.73e-173: 485: 67.89		RGS13_HUMAN (18-180): 8.58e-59: 197: 17.79
+	Hs
		180650 GNAI2_HUMAN (1-354): 9.73e-173: 485: 67.89		RGS16_HUMAN (1-171): 2.61e-57: 195: 17.78
+	Hs
		180657 GNAI1_HUMAN (1-354): 2.77e-172: 484: 69.01		RGS16_HUMAN (1-171): 2.61e-57: 195: 17.78
+	Hs
		450988 GNAO_HUMAN (1-354): 6.79e-174: 489: 82.20		RGS19_HUMAN (29-181): 1.28e-51: 180: 20.13
+	Hs
		391356 GNAI2_HUMAN (1-354): 9.73e-173: 485: 67.89		RGS19_HUMAN (29-181): 1.28e-51: 180: 20.13