Interactor 1: ODPA (P16387)
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial (EC 1.2.4.1) (Pyruvate dehydrogenase complex component E1 alpha) (PDHE1-A)
Gene: PDA1

Interactor 2: ODPB (P32473)
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (EC 1.2.4.1) (Pyruvate dehydrogenase complex component E1 beta) (PDHE1-B)
Gene: PDB1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.892

The method score is based on:

Property Details
Experiments 11805826, 16429126, 32051233, 37968396
Identification Methods tandem affinity purification, affinity chromatography technology, cross-linking study
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains E1_dh~Transket_pyr, E1_dh~Transketolase_C
Common GO terms GO:0004739 - pyruvate dehydrogenase (acetyl-transferring) activity
GO:0005739 - mitochondrion
GO:0006086 - acetyl-CoA biosynthetic process from pyruvate
GO:0042645 - mitochondrial nucleoid
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 420
Sc

1 366
+ Dm
+ Mm
+ Hs
+ At
+ Dm
+ Hs
+ Ce
+ At
+ Hs
+ Ce
+ Ce
+ Pp
+ Gs
+ Tt
+ Mp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024