HitPredict

Interactor 1: H15 (P16401)
Histone H1.5 (Histone H1a) (Histone H1b) (Histone H1s-3)
Gene: H1-5

Interactor 2: H2A2B (Q8IUE6)
Histone H2A type 2-B (H2A-clustered histone 21)
Gene: H2AC21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	30021884, 33961781
Identification Methods	proximity labelling technology, affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0030527 - structural constituent of chromatin GO:0031492 - nucleosomal DNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 226 Hs			1 130
+	Hs
		391708 SHPRH_HUMAN (14-189): 3.16e-65: 220: 27.12		H2A1B_HUMAN (1-130): 1e-67: 202: 93.85
+	Hs
		608582 H1T_HUMAN (1-214): 6.06e-27: 104: 50.00		H2A2B_HUMAN (1-130): 2.22e-71: 211: 100.00
+	Hs
		391547 H1T_HUMAN (1-214): 6.06e-27: 104: 50.00		H2A1B_HUMAN (1-130): 1e-67: 202: 93.85
+	Hs
		470268 H1T_HUMAN (1-214): 6.06e-27: 104: 50.00		H2A1_HUMAN (1-130): 8.04e-68: 202: 94.62
+	Hs
		608562 H1T_HUMAN (1-214): 6.06e-27: 104: 50.00		H2A2C_HUMAN (1-127): 3.2e-67: 200: 96.06
+	Hs
		555292 H1T_HUMAN (1-214): 6.06e-27: 104: 50.00		H2AX_HUMAN (1-123): 4.57e-66: 198: 95.94
+	Hs
		470252 H13_HUMAN (1-184): 1.62e-22: 93.3: 68.48		H2A1_HUMAN (1-130): 8.04e-68: 202: 94.62
+	Hs
		559478 H13_HUMAN (1-184): 1.62e-22: 93.3: 68.48		H2A1J_HUMAN (1-128): 6.6e-68: 202: 95.31
+	Hs
		559808 H12_HUMAN (32-174): 1.09e-17: 80.2: 75.17		H2A2B_HUMAN (1-130): 2.22e-71: 211: 100.00
+	Hs
		391534 H15_HUMAN (1-118): 3.29e-18: 81.7: 100.00		H2A1B_HUMAN (1-130): 1e-67: 202: 93.85
+	Hs
		470251 H15_HUMAN (1-118): 3.29e-18: 81.7: 100.00		H2A1_HUMAN (1-130): 8.04e-68: 202: 94.62
+	Hs
		559216 H15_HUMAN (1-118): 3.29e-18: 81.7: 100.00		H2A1H_HUMAN (1-128): 7.7e-68: 202: 95.31
+	Hs
		391535 H12_HUMAN (32-174): 1.09e-17: 80.2: 75.17		H2A1B_HUMAN (1-130): 1e-67: 202: 93.85
+	Hs
		470253 H12_HUMAN (32-174): 1.09e-17: 80.2: 75.17		H2A1_HUMAN (1-130): 8.04e-68: 202: 94.62
+	Hs
		559894 H12_HUMAN (32-174): 1.09e-17: 80.2: 75.17		H2A1H_HUMAN (1-128): 7.7e-68: 202: 95.31
+	Hs
		559911 H12_HUMAN (32-174): 1.09e-17: 80.2: 75.17		H2A1J_HUMAN (1-128): 6.6e-68: 202: 95.31
+	Dm
		355231 H1_DROME (2-225): 1.13e-26: 104: 32.89		H2A_DROME (17-122): 2.2e-58: 178: 93.40
+	Hs
		559111 H15_HUMAN (1-118): 3.29e-18: 81.7: 100.00		H2A2C_HUMAN (1-127): 3.2e-67: 200: 96.06
+	Hs
		470240 H14_HUMAN (1-118): 3.82e-17: 78.6: 87.29		H2A1_HUMAN (1-130): 8.04e-68: 202: 94.62
+	Hs
		555279 H12_HUMAN (32-174): 1.09e-17: 80.2: 75.17		H2AX_HUMAN (1-123): 4.57e-66: 198: 95.94