HitPredict

Interactor 1: H12 (P16403)
Histone H1.2 (Histone H1c) (Histone H1d) (Histone H1s-1)
Gene: H1-2

Interactor 2: YBOX1 (P67809)
Y-box-binding protein 1 (YB-1) (CCAAT-binding transcription factor I subunit A) (CBF-A) (DNA-binding protein B) (DBPB) (Enhancer factor I subunit A) (EFI-A) (Nuclease-sensitive element-binding protein 1) (Y-box transcription factor)
Gene: YBX1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	33961781, 18258596, 23986595, 25497084
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003690 - double-stranded DNA binding GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 213 Hs			1 324
+	Hs
		559377 H13_HUMAN (1-181): 4.78e-25: 99.5: 82.42		YBOX1_HUMAN (1-324): 4.21e-69: 220: 100.00
+	Hs
		608532 H1T_HUMAN (1-183): 5.25e-24: 96.4: 53.40		YBOX1_HUMAN (1-324): 4.21e-69: 220: 100.00
+	Hs
		488993 H14_HUMAN (1-172): 4.96e-18: 80.6: 88.37		YBOX1_HUMAN (1-324): 4.21e-69: 220: 100.00
+	Hs
		559057 H15_HUMAN (1-157): 2.05e-15: 74.1: 76.25		YBOX1_HUMAN (1-324): 4.21e-69: 220: 100.00
+	Hs
		931103 H11_HUMAN (38-182): 2.87e-15: 73.3: 62.07		YBOX1_HUMAN (1-324): 4.21e-69: 220: 100.00
+	Hs
		559432 H13_HUMAN (1-181): 4.78e-25: 99.5: 82.42		LN28B_HUMAN (33-275): 3.38e-55: 182: 24.41
+	Hs
		608572 H1T_HUMAN (1-183): 5.25e-24: 96.4: 53.40		LN28B_HUMAN (33-275): 3.38e-55: 182: 24.41
+	Hs
		559780 H12_HUMAN (1-173): 1.53e-22: 92.6: 100.00		LN28B_HUMAN (33-275): 3.38e-55: 182: 24.41
+	Hs
		488890 H14_HUMAN (1-172): 4.96e-18: 80.6: 88.37		YBOX3_HUMAN (46-324): 2.21e-55: 186: 51.69
+	Hs
		559528 H13_HUMAN (1-181): 4.78e-25: 99.5: 82.42		YBOX2_HUMAN (23-314): 7.22e-48: 166: 44.15
+	Hs
		608664 H1T_HUMAN (1-183): 5.25e-24: 96.4: 53.40		YBOX2_HUMAN (23-314): 7.22e-48: 166: 44.15
+	Hs
		558973 H15_HUMAN (1-157): 2.05e-15: 74.1: 76.25		YBOX3_HUMAN (46-324): 2.21e-55: 186: 51.69
+	Hs
		563074 H11_HUMAN (38-182): 2.87e-15: 73.3: 62.07		YBOX3_HUMAN (46-324): 2.21e-55: 186: 51.69
+	Hs
		560019 H12_HUMAN (1-173): 1.53e-22: 92.6: 100.00		YBOX2_HUMAN (23-314): 7.22e-48: 166: 44.15
+	Hs
		559498 H13_HUMAN (1-181): 4.78e-25: 99.5: 82.42		LN28A_HUMAN (50-217): 1.06e-42: 148: 23.46
+	Hs
		489348 H14_HUMAN (1-172): 4.96e-18: 80.6: 88.37		YBOX2_HUMAN (23-314): 7.22e-48: 166: 44.15
+	Hs
		608641 H1T_HUMAN (1-183): 5.25e-24: 96.4: 53.40		LN28A_HUMAN (50-217): 1.06e-42: 148: 23.46
+	Hs
		559955 H12_HUMAN (1-173): 1.53e-22: 92.6: 100.00		LN28A_HUMAN (50-217): 1.06e-42: 148: 23.46
+	Hs
		489286 H14_HUMAN (1-172): 4.96e-18: 80.6: 88.37		LN28A_HUMAN (50-217): 1.06e-42: 148: 23.46
+	Hs
		559252 H15_HUMAN (1-157): 2.05e-15: 74.1: 76.25		LN28A_HUMAN (50-217): 1.06e-42: 148: 23.46