HitPredict

Interactor 1: H12 (P16403)
Histone H1.2 (Histone H1c) (Histone H1d) (Histone H1s-1)
Gene: H1-2

Interactor 2: CDK5 (Q00535)
Cyclin-dependent kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Cyclin-dependent-like kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)
Gene: CDK5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 213 Hs			1 292
+	Rn
		413197 H1T_RAT (1-196): 4.89e-32: 117: 48.99		Q6P751_RAT (1-292): 2.27e-143: 406: 59.73
+	Hs
		559328 H13_HUMAN (1-181): 4.78e-25: 99.5: 82.42		CDK2_HUMAN (1-292): 2.7e-143: 406: 59.39
+	Rn
		88903 H11_RAT (1-120): 3.04e-19: 84.1: 68.85		Q6P751_RAT (1-292): 2.27e-143: 406: 59.73
+	Hs
		414717 H13_HUMAN (1-181): 4.78e-25: 99.5: 82.42		CDK1_HUMAN (1-289): 1.13e-134: 384: 56.01
+	Hs
		558990 H15_HUMAN (1-157): 2.05e-15: 74.1: 76.25		CDK2_HUMAN (1-292): 2.7e-143: 406: 59.39
+	Hs
		625377 H11_HUMAN (38-182): 2.87e-15: 73.3: 62.07		CDK2_HUMAN (1-292): 2.7e-143: 406: 59.39
+	Hs
		489003 H14_HUMAN (1-172): 4.96e-18: 80.6: 88.37		CDK5_HUMAN (1-292): 6.09e-139: 395: 100.00
+	Mm
		794656 H15_MOUSE (1-202): 3.97e-20: 86.4: 67.16		CDK2_MOUSE (1-292): 7.36e-136: 389: 51.77
+	Hs
		559065 H15_HUMAN (1-157): 2.05e-15: 74.1: 76.25		CDK5_HUMAN (1-292): 6.09e-139: 395: 100.00
+	Hs
		960270 H11_HUMAN (38-182): 2.87e-15: 73.3: 62.07		CDK5_HUMAN (1-292): 6.09e-139: 395: 100.00
+	Rn
		88899 H11_RAT (1-120): 3.04e-19: 84.1: 68.85		CDK1_RAT (1-289): 2.13e-134: 383: 56.70
+	Hs
		559352 H13_HUMAN (1-181): 4.78e-25: 99.5: 82.42		CDK7_HUMAN (2-292): 2.63e-127: 367: 45.24
+	Mm
		794639 H11_MOUSE (1-121): 1.59e-14: 71.4: 69.11		CDK5_MOUSE (1-292): 9.13e-139: 394: 99.66
+	Mm
		794643 H11_MOUSE (1-121): 1.59e-14: 71.4: 69.11		CDK2_MOUSE (1-292): 7.36e-136: 389: 51.77
+	Hs
		559612 H12_HUMAN (1-173): 1.53e-22: 92.6: 100.00		CDK7_HUMAN (2-292): 2.63e-127: 367: 45.24
+	Hs
		414716 H15_HUMAN (1-157): 2.05e-15: 74.1: 76.25		CDK1_HUMAN (1-289): 1.13e-134: 384: 56.01
+	Hs
		414874 H11_HUMAN (38-182): 2.87e-15: 73.3: 62.07		CDK1_HUMAN (1-289): 1.13e-134: 384: 56.01
+	Mm
		509472 H11_MOUSE (1-121): 1.59e-14: 71.4: 69.11		CDK1_MOUSE (1-289): 2.16e-133: 381: 56.70
+	Hs
		488949 H14_HUMAN (1-172): 4.96e-18: 80.6: 88.37		CDK7_HUMAN (2-292): 2.63e-127: 367: 45.24
+	Hs
		841171 H11_HUMAN (38-182): 2.87e-15: 73.3: 62.07		CDK7_HUMAN (2-292): 2.63e-127: 367: 45.24