HitPredict

Interactor 1: H12 (P16403)
Histone H1.2 (Histone H1c) (Histone H1d) (Histone H1s-1)
Gene: H1-2

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 213 Hs			1 768
+	Hs
		559401 H13_HUMAN (1-181): 4.78e-25: 99.5: 82.42		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Mm
		794677 H13_MOUSE (1-115): 1.66e-15: 74.1: 89.66		CUL3_MOUSE (1-768): 0: 949: 99.48
+	Hs
		559699 H12_HUMAN (1-173): 1.53e-22: 92.6: 100.00		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		559700 H12_HUMAN (1-173): 1.53e-22: 92.6: 100.00		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		971164 H11_HUMAN (38-182): 2.87e-15: 73.3: 62.07		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		559696 H12_HUMAN (1-173): 1.53e-22: 92.6: 100.00		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		559697 H12_HUMAN (1-173): 1.53e-22: 92.6: 100.00		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		559877 H12_HUMAN (1-173): 1.53e-22: 92.6: 100.00		CUL5_HUMAN (25-768): 0: 597: 23.77