HitPredict

Interactor 1: H12 (P16403)
Histone H1.2 (Histone H1c) (Histone H1d) (Histone H1s-1)
Gene: H1-2

Interactor 2: SET1B (Q9UPS6)
Histone-lysine N-methyltransferase SETD1B (EC 2.1.1.364) (Lysine N-methyltransferase 2G) (SET domain-containing protein 1B) (hSET1B)
Gene: SETD1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 213 Hs			1 1966
+	Hs
		971403 H11_HUMAN (38-182): 2.87e-15: 73.3: 62.07		SET1B_HUMAN (1-1966): 3.57e-162: 549: 100.00
+	Mm
		990819 H1T_MOUSE (1-196): 2.23e-34: 123: 49.50		EZH2_MOUSE (1461-1949): 4.71e-65: 239: 15.18
+	Hs
		559663 H12_HUMAN (1-173): 1.53e-22: 92.6: 100.00		KMT2A_HUMAN (1173-1966): 2.68e-66: 252: 21.73
+	Hs
		559417 H13_HUMAN (1-181): 4.78e-25: 99.5: 82.42		EZH2_HUMAN (1464-1949): 9.8e-64: 235: 15.84
+	Hs
		489011 H14_HUMAN (1-172): 4.96e-18: 80.6: 88.37		KMT2A_HUMAN (1173-1966): 2.68e-66: 252: 21.73
+	Hs
		971335 H11_HUMAN (38-182): 2.87e-15: 73.3: 62.07		NSD3_HUMAN (1721-1965): 3.64e-68: 256: 24.90
+	Hs
		559730 H12_HUMAN (1-173): 1.53e-22: 92.6: 100.00		EZH2_HUMAN (1464-1949): 9.8e-64: 235: 15.84
+	Hs
		331717 H12_HUMAN (1-173): 1.53e-22: 92.6: 100.00		NSD2_HUMAN (1654-1965): 6.33e-60: 230: 22.15
+	Hs
		559470 H13_HUMAN (1-181): 4.78e-25: 99.5: 82.42		NSD1_HUMAN (1721-1965): 2.24e-57: 223: 23.70
+	Hs
		559895 H12_HUMAN (1-173): 1.53e-22: 92.6: 100.00		NSD1_HUMAN (1721-1965): 2.24e-57: 223: 23.70
+	Hs
		331706 H14_HUMAN (1-172): 4.96e-18: 80.6: 88.37		NSD2_HUMAN (1654-1965): 6.33e-60: 230: 22.15
+	Hs
		559109 H15_HUMAN (1-157): 2.05e-15: 74.1: 76.25		EZH2_HUMAN (1464-1949): 9.8e-64: 235: 15.84
+	Hs
		971187 H11_HUMAN (38-182): 2.87e-15: 73.3: 62.07		EZH2_HUMAN (1464-1949): 9.8e-64: 235: 15.84
+	Hs
		331716 H15_HUMAN (1-157): 2.05e-15: 74.1: 76.25		NSD2_HUMAN (1654-1965): 6.33e-60: 230: 22.15
+	Hs
		489205 H14_HUMAN (1-172): 4.96e-18: 80.6: 88.37		NSD1_HUMAN (1721-1965): 2.24e-57: 223: 23.70
+	Hs
		331791 H11_HUMAN (38-182): 2.87e-15: 73.3: 62.07		NSD2_HUMAN (1654-1965): 6.33e-60: 230: 22.15
+	Hs
		559217 H15_HUMAN (1-157): 2.05e-15: 74.1: 76.25		NSD1_HUMAN (1721-1965): 2.24e-57: 223: 23.70