HitPredict

Interactor 1: CTLA4 (P16410)
Cytotoxic T-lymphocyte protein 4 (Cytotoxic T-lymphocyte-associated antigen 4) (CTLA-4) (CD antigen CD152)
Gene: CTLA4

Interactor 2: AP2M1 (Q96CW1)
AP-2 complex subunit mu (AP-2 mu chain) (Adaptin-mu2) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Plasma membrane adaptor AP-2 50 kDa protein)
Gene: AP2M1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.688

Property	Details
Experiments	11583591, 9812899, 9200449, 16476059
Identification Methods	x-ray crystallography, affinity chromatography technology, pull down, two hybrid
Interaction Type	association, physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0045334 - clathrin-coated endocytic vesicle
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 223 Hs			1 435
+	Mm
		454882 CTLA4_MOUSE (1-223): 3.07e-107: 309: 74.44		AP2M1_MOUSE (1-435): 1.03e-178: 507: 100.00