HitPredict

Interactor 1: BIP (P16474)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein homolog) (GRP-78) (Immunoglobulin heavy chain-binding protein homolog) (BiP)
Gene: KAR2

Interactor 2: SIL1 (Q08199)
Nucleotide exchange factor SIL1 (Protein SLS1)
Gene: SIL1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.90	0.904

Property	Details
Experiments	20430899, 14704430, 12052876, 11101517, 10958688, 21675960
Identification Methods	affinity chromatography technology, pull down, two hybrid, x-ray crystallography
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	HSP70~SIL1
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005788 - endoplasmic reticulum lumen GO:0006616 - SRP-dependent cotranslational protein targeting to membrane, translocation
Homologous interactions	0