HitPredict

Interactor 1: SPTN1 (P16546)
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain)
Gene: Sptan1

Interactor 2: AGAP2 (Q3UHD9)
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 (AGAP-2) (Centaurin-gamma-1) (Cnt-g1) (Phosphatidylinositol 3-kinase enhancer) (PIKE)
Gene: AGAP2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	28706196
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Ank_2~EF-hand_7, Ank_2~SH3_1
Common GO terms	GO:0005829 - cytosol GO:0030036 - actin cytoskeleton organization GO:0044877 - protein-containing complex binding GO:0098794 - postsynapse GO:0098978 - glutamatergic synapse
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 2472 Mm			1 1186
+	Mm
		82757 B9EKJ1_MOUSE (1-2472): 0: 692: 99.76		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		1112582 SPTB2_MOUSE (1-1503): 2.83e-66: 252: 22.55		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		1112587 Q68FG2_MOUSE (1-1506): 1.1e-57: 224: 23.68		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		1112660 MACF1_MOUSE (707-2370): 6.79e-24: 113: 9.72		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		1112601 ACTN1_MOUSE (1862-2210): 2.76e-10: 68.2: 21.99		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		885077 ACTN4_MOUSE (1843-2219): 8.52e-10: 66.6: 20.30		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Hs
		521541 ACTN1_HUMAN (1862-2210): 4.47e-11: 70.9: 22.25		GIT2_HUMAN (932-1139): 1.58e-73: 262: 31.98