HitPredict

Interactor 1: AT2A2 (P16615)
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) (SR Ca(2+)-ATPase 2) (EC 7.2.2.10) (Calcium pump 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase)
Gene: ATP2A2

Interactor 2: TNR1A (P19438)
Tumor necrosis factor receptor superfamily member 1A (Tumor necrosis factor receptor 1) (TNF-R1) (Tumor necrosis factor receptor type I) (TNF-RI) (TNFR-I) (p55) (p60) (CD antigen CD120a) [Cleaved into: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)]
Gene: TNFRSF1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	14743216
Identification Methods	tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1042 Hs			1 455
+	Hs
		393028 AT1A1_HUMAN (3-997): 0: 797: 26.72		TNR1A_HUMAN (1-455): 1.34e-147: 430: 100.00
+	Hs
		561497 AT2A2_HUMAN (1-1042): 0: 1060: 100.00		TNR1B_HUMAN (7-287): 3.18e-45: 165: 19.86
+	Hs
		163746 AT2A1_HUMAN (1-1000): 0: 961: 83.72		TNR1B_HUMAN (7-287): 3.18e-45: 165: 19.86
+	Hs
		639624 AT2A3_HUMAN (1-997): 0: 956: 76.85		TNR5_HUMAN (38-315): 1.92e-46: 163: 19.64
+	Hs
		645813 AT2A3_HUMAN (1-997): 0: 956: 76.85		CD27_HUMAN (42-281): 3.74e-29: 116: 16.87
+	Hs
		393030 AT1A1_HUMAN (3-997): 0: 797: 26.72		TNR1B_HUMAN (7-287): 3.18e-45: 165: 19.86
+	Hs
		619289 AT2B4_HUMAN (3-1028): 0: 762: 25.75		TNR27_HUMAN (44-318): 2.26e-41: 150: 18.24
+	Hs
		530873 AT1A3_HUMAN (4-997): 0: 794: 26.55		TNR9_HUMAN (56-221): 5.56e-20: 90.8: 16.87
+	Hs
		155882 AT1A3_HUMAN (4-997): 0: 794: 26.55		TR10C_HUMAN (29-171): 1.03e-19: 90.4: 24.83