HitPredict

Interactor 1: AT2A2 (P16615)
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) (SR Ca(2+)-ATPase 2) (EC 7.2.2.10) (Calcium pump 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase)
Gene: ATP2A2

Interactor 2: CALX (P27824)
Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
Gene: CANX

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	35271311, 20528919
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0016020 - membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1042 Hs			1 592
+	Mm
		223152 AT2A2_MOUSE (1-1042): 0: 1047: 98.66		CALX_MOUSE (1-592): 0: 732: 90.56
+	Hs
		163753 AT2A1_HUMAN (1-1000): 0: 961: 83.72		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		160969 AT2A1_HUMAN (1-1000): 0: 961: 83.72		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		393052 AT1A1_HUMAN (3-997): 0: 797: 26.72		CALX_HUMAN (1-592): 0: 786: 100.00
+	Dm
		611111 ATC1_DROME (1-993): 0: 913: 72.13		Q9VAL7_DROME (33-592): 0: 633: 49.74
+	Mm
		223147 AT2A2_MOUSE (1-1042): 0: 1047: 98.66		CALR_MOUSE (67-470): 1.96e-145: 428: 37.59