HitPredict

Interactor 1: AT2A2 (P16615)
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) (SR Ca(2+)-ATPase 2) (EC 7.2.2.10) (Calcium pump 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase)
Gene: ATP2A2

Interactor 2: CDK9 (P50750)
Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)
Gene: CDK9

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	27684187, 26209609
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0016020 - membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1042 Hs			1 372
+	Hs
		561563 AT2A2_HUMAN (1-1042): 0: 1060: 100.00		MK07_HUMAN (12-372): 2.64e-131: 396: 29.75
+	Hs
		414719 AT2A2_HUMAN (1-1042): 0: 1060: 100.00		CDK1_HUMAN (16-315): 5.07e-124: 361: 40.40
+	Hs
		625542 AT2A3_HUMAN (1-997): 0: 956: 76.85		CDK2_HUMAN (16-321): 4.46e-136: 391: 38.76
+	Hs
		393104 AT1A1_HUMAN (3-997): 0: 797: 26.72		CDK9_HUMAN (1-372): 2.88e-147: 422: 100.00
+	Hs
		393182 AT1A1_HUMAN (3-997): 0: 797: 26.72		MK07_HUMAN (12-372): 2.64e-131: 396: 29.75
+	Hs
		393042 AT1A1_HUMAN (3-997): 0: 797: 26.72		CDK2_HUMAN (16-321): 4.46e-136: 391: 38.76
+	Hs
		393048 AT1A1_HUMAN (3-997): 0: 797: 26.72		MK03_HUMAN (1-359): 1.92e-131: 382: 30.36
+	Hs
		393055 AT1A1_HUMAN (3-997): 0: 797: 26.72		MK01_HUMAN (5-359): 1.35e-131: 382: 30.99
+	Rn
		416170 AT1A3_RAT (4-997): 0: 793: 26.55		MK03_RAT (9-362): 2.63e-130: 379: 30.79