HitPredict

Interactor 1: AT2A2 (P16615)
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) (SR Ca(2+)-ATPase 2) (EC 7.2.2.10) (Calcium pump 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase)
Gene: ATP2A2

Interactor 2: TTC3 (P53804)
E3 ubiquitin-protein ligase TTC3 (EC 2.3.2.27) (Protein DCRR1) (RING finger protein 105) (RING-type E3 ubiquitin transferase TTC3) (TPR repeat protein D) (Tetratricopeptide repeat protein 3) (TPR repeat protein 3)
Gene: TTC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.50	0.494

Property	Details
Experiments	35914814
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1042 Hs			1 2025
+	Hs
		163833 AT2A1_HUMAN (1-1000): 0: 961: 83.72		TGO1_HUMAN (1104-1863): 1.22e-83: 308: 14.29
+	Hs
		561666 AT2A2_HUMAN (1-1042): 0: 1060: 100.00		Q9BPW0_HUMAN (220-360): 5.96e-43: 167: 29.79
+	Hs
		561506 AT2A2_HUMAN (1-1042): 0: 1060: 100.00		STIP1_HUMAN (74-510): 1.57e-24: 112: 13.23
+	Hs
		393068 AT1A1_HUMAN (3-997): 0: 797: 26.72		STIP1_HUMAN (74-510): 1.57e-24: 112: 13.23
+	Dm
		530331 ATNA_DROME (3-997): 0: 761: 26.07		Q9VH81_DROME (231-348): 2.45e-32: 136: 34.75
+	Dm
		1214118 Q8IPS6_DROME (4-988): 3.13e-141: 448: 32.60		Q9VH81_DROME (231-348): 2.45e-32: 136: 34.75