HitPredict

Interactor 1: AT2A2 (P16615)
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) (SR Ca(2+)-ATPase 2) (EC 7.2.2.10) (Calcium pump 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase)
Gene: ATP2A2

Interactor 2: TAP2 (Q03519)
Antigen peptide transporter 2 (APT2) (EC 7.4.2.14) (ATP-binding cassette sub-family B member 3) (Peptide supply factor 2) (Peptide transporter PSF2) (PSF-2) (Peptide transporter TAP2) (Peptide transporter involved in antigen processing 2) (Really interesting new gene 11 protein) (RING11)
Gene: TAP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35961308
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0016020 - membrane GO:0016887 - ATP hydrolysis activity
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1042 Hs			1 686
+	Hs
		561558 AT2A2_HUMAN (1-1042): 0: 1060: 100.00		TAP1_HUMAN (23-685): 2.59e-151: 458: 36.72
+	Hs
		164007 AT2A1_HUMAN (1-1000): 0: 961: 83.72		MITOS_HUMAN (13-685): 3.04e-158: 476: 32.76
+	Hs
		393170 AT1A1_HUMAN (3-997): 0: 797: 26.72		TAP2_HUMAN (1-682): 0: 614: 100.00
+	Hs
		163757 AT2A1_HUMAN (1-1000): 0: 961: 83.72		MRP1_HUMAN (72-685): 3.58e-60: 221: 16.35
+	Dm
		611085 ATC1_DROME (1-993): 0: 913: 72.13		Q7KTD0_DROME (144-685): 3.98e-59: 218: 15.43
+	Dm
		530302 ATNA_DROME (3-997): 0: 761: 26.07		Q7KTD0_DROME (144-685): 3.98e-59: 218: 15.43