HitPredict

Interactor 1: AT2A2 (P16615)
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) (SR Ca(2+)-ATPase 2) (EC 7.2.2.10) (Calcium pump 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase)
Gene: ATP2A2

Interactor 2: VAPA (Q9P0L0)
Vesicle-associated membrane protein-associated protein A (VAMP-A) (VAMP-associated protein A) (VAP-A) (33 kDa VAMP-associated protein) (VAP-33)
Gene: VAPA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1042 Hs			1 249
+	Hs
		310495 AT2A2_HUMAN (1-1042): 0: 1060: 100.00		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Hs
		164021 AT2A1_HUMAN (1-1000): 0: 961: 83.72		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		1274543 AT2A3_HUMAN (1-997): 0: 956: 76.85		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		163702 AT2A1_HUMAN (1-1000): 0: 961: 83.72		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Hs
		163893 AT2A1_HUMAN (1-1000): 0: 961: 83.72		MSPD2_HUMAN (14-190): 1.24e-39: 144: 19.34