HitPredict

Interactor 1: LAR (P16621)
Tyrosine-protein phosphatase Lar (EC 3.1.3.48) (Protein-tyrosine-phosphate phosphohydrolase) (dLAR)
Gene: LAR

Interactor 2: ENA (Q8T4F7)
Protein enabled
Gene: ENA

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.653

Property	Details
Experiments	10069336, 16476662
Identification Methods	affinity chromatography technology, enzymatic study, pull down, phosphatase assay
Interaction Type	physical association, direct interaction, dephosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007411 - axon guidance GO:0030424 - axon GO:0031252 - cell leading edge GO:0051491 - positive regulation of filopodium assembly
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 2029 Dm			1 980
+	Dm
		561761 PTP69_DROME (47-583): 8.4e-19: 96.2: 13.55		ENA_DROME (1-980): 3.38e-153: 480: 100.00
+	Dm
		729775 PTP10_DROME (1039-1403): 4.82e-11: 70.8: 15.30		ENA_DROME (1-980): 3.38e-153: 480: 100.00
+	Hs
		490001 PTPRF_HUMAN (2-915): 6.76e-81: 299: 19.01		CBP_HUMAN (410-859): 5.16e-25: 115: 18.24