Interactor 1: SYP (P16659)
Proline--tRNA ligase (EC 6.1.1.15) (Global RNA synthesis factor) (Prolyl-tRNA synthetase) (ProRS)
Gene: proS

Interactor 2: SYP (P16659)
Proline--tRNA ligase (EC 6.1.1.15) (Global RNA synthesis factor) (Prolyl-tRNA synthetase) (ProRS)
Gene: proS

Species: Escherichia coli K-12

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 16858726
Identification Methods blue native page
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HGTP_anticodon~HGTP_anticodon, HGTP_anticodon~tRNA-synt_2b, tRNA-synt_2b~tRNA-synt_2b, tRNA_edit~tRNA_edit
Common GO terms GO:0004827 - proline-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006433 - prolyl-tRNA aminoacylation
GO:0043906 - Ala-tRNA(Pro) hydrolase activity
and 1 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 572
Ec

1 572
+ Hp
+ Hs
+ Ca
+ Hs
+ Dm
+ Hs
+ Pf
+ Ec
+ Sc
+ Sc
+ Hs
+ Hs
+ Hs
+ Ec
+ Sc

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Last updated: 15 Jul 2024