Interactor 1: PLCG2 (P16885)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-2) (Phospholipase C-IV) (PLC-IV) (Phospholipase C-gamma-2) (PLC-gamma-2)
Gene: PLCG2

Interactor 2: PLCG2 (P16885)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-2) (Phospholipase C-IV) (PLC-IV) (Phospholipase C-gamma-2) (PLC-gamma-2)
Gene: PLCG2

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 10469124
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C2~C2, C2~PI-PLC-X, C2~PI-PLC-Y, C2~SH2, PI-PLC-X~PI-PLC-X, PI-PLC-X~PI-PLC-Y, SH2~SH2, SH2~SH3_1, SH3_1~SH3_1
Common GO terms GO:0001775 - cell activation
GO:0001784 - phosphotyrosine residue binding
GO:0001878 - response to yeast
GO:0002092 - positive regulation of receptor internalization
GO:0002223 - stimulatory C-type lectin receptor signaling pathway
and 64 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1265
Hs

1 1265
+ Hs
+ Rn
+ Bt
+ Hs
+ Hs

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Last updated: 15 Jul 2024