Interactor 1: GLP1 (P13508)
Protein glp-1 [Cleaved into: glp-1/Notch intracellular domain]
Gene: glp-1
Interactor 2: LAG3 (Q09260)
Protein lag-3 (Abnormal cell lineage protein 3) (Abnormal germline proliferation protein 3)
Gene: sel-8
Species: Caenorhabditis elegans
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.621 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10830967 |
| Identification Methods | two hybrid |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Activator_LAG-3~Ank_2 |
| Common GO terms | GO:0003713 - transcription coactivator activity GO:0007219 - Notch signaling pathway GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0090575 - RNA polymerase II transcription regulator complex GO:2000648 - positive regulation of stem cell proliferation |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
